Félix García Sánchez
BIOGRAPHICAL SKETCHProvide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. | |||
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NAME Felix Garcia-Sanchez | POSITION TITLE Senior Faculty in Immunology | ||
eRA COMMONS USER NAME
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EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) | |||
INSTITUTION AND LOCATION | DEGREE (if applicable) | YEAR(s) | FIELD OF STUDY |
UniverisadComplutense de Madrid | B.S. | 1990 | Biological Sciences |
UniverisadComplutense de Madrid | Ph.D. | 1994 | Biology |
Ministerio de Sanidad / Ministerio de Educación | Specialist in Immunology | 2000 | Clinical Immunology |
A. Positions and Honors
Positions and Employment
1995-1996 Post-doctoral Associate, M.D Anderson Cancer Center / Molecular Hematology
1996-1997 Post-doctoral Associate, Yale University School of Medicine / Clinical Oncology Division
1997-2001 Faculty in Immunology. Blood Transfusion Centre. Madrid. Spain.
2001-2005 Specialist Faculty in Immunology. Blood Transfusion Centre. Madrid. Spain
2005- Senior Faculty in Immunology. Blood Transfusion Centre. Madrid. Spain.
2007- Honorary Professor. Immunology Dpt School of Medicine. University Complutense of Madrid
C. 15 Selected Peer-Reviewed Publications (of 89 Total).
1. S.Q. Fu, F. García-Sánchez, I. Chung, A.B. Deisseroth. Adenoviral Vectors and Hematopoietic cells.Blood 88, 1460-1461, 1996.
2. S. Santos, A. Balas, R. Lillo, F. García-Sánchez, J.L. Merino, J.L. Vicario. HLA-B14 subtyping by semi-nested PCR-SSP and haplotype distribution in a Spanish population. Tissue Antigens 50, 671-674, 1997.
3. M.A. Diaz, F. García-Sánchez, J.L. Vicario, M. Ramírez, A. Balas, L. Madero. Clinical relevance of T-Cell receptor delta gene rearrangement in childhood B-precursor cells acute lymphoblastic leukemia. Br J Haematol 99, 308-313, 1997.
4. Fujii T, Fu SQ, Yin LH, Nanakorn T, García-Sánchez F, Cooperberg M, Guo D, Wang T.D.L, Pizzorno G, Deisseroth A. Multidrug Resistance and Prodrug activation for cancer gene therapy of Breast Cancer. BreastCancer 4, 210-212, 1997.
5. F. Garcia-Sánchez, G. Pizzorno, SQ Fu, T Nanakor, D. S. Krause, J. Liang, E. Adams, JJ. Leffert, , L.H. Yin, M.R. Cooperberg, E. Hannania, W.L. Wang, J.H. Won, X.Y. Peng, R. Cote, R. Brown, B Burtness, R. Giles, R. Crystal, A. B. Deisseroth. Cytosine deaminase adenoviral vector and 5-fluorocytosine selectively reduce breast cancer cells 1 million-fold when they contaminate hematopoietic cells: a potential method for autologous transplantation. Blood 92, 672-682, 1998
6. González-Requejo A, Madero L, Díaz MA, Villa M, García-Escribano C, Balas A, Lillo R, García-Sánchez F, Vicario JL. Progenitor cell subsets and engraftment kinetics in children undergoing autologous peripheral blood stem cell transplantation.Br J Haematol 101, 104-110, 1998.
7. Balas A, Avilés MJ, García-Sánchez F, Vicario JL. Description of a New Mutation in the L-Ferritin Iron-Responsive Element Associated with Hereditary Hyperferritinemia-Cataract Syndrome in a Spanish Family.Blood 93, 4020-4021, 1999.
8. García-Castro J, Segovia JC, García-Sánchez F, Lillo R, Gómez-Navarro J, Curiel DT, Bueren JA. Selective transduction of murine myelomonocytic leukemia cells (WEHI-3B) with regular and RGD-adenoviral vectors. Molecular Therapy 3, 70-77, 2001.
9. Wright N, de Lera TL, García-Moruja C, Lillo R, García-Sánchez F, Caruz A, Teixidó J. Transforming growth factor-beta 1 down regulates expressión of chemokine stromal cell-derived factor 1: Functional consequences in cell migration and adhesion. Blood 102, 1978-1984, 2003.
10. García-Castro, Rio P, Lillo R, García-Sánchez F, Segovia JC, Bueren JA. Purgingofleukemia-contaminatedbonemarrowgraftsusing suicide adenoviralvectors: an in vivo murine experimental model. Gene Therapy 10, 1328-1335, 2003.
11. García-Castro, Martínez-Palacio J, Lillo R, García-Sánchez F, Alemany R, Madero L, Bueren JÁ, Ramírez M. Tumor cells as cellularvehiclestodeliver gene therapiestometastatictumors. Cancer Gene Therapy 12, 341-349, 2005.
12. Cervera A, Lillo R, García-Sánchez F, Madero L, Madero R, Vicario JL. Flow cytometric assessment of hematopoietic cell subsets in cryopreserved preterm and term cord blood. Influence of obstetrical parameters, and availability for transplantation. Am J Hematol 81, 397-410, 2006.
13. Balas A, Vilches C, Rodríguez MA, Fernández B, Martínez MP, de Pablo R, García-Sánchez F, Vicario JL.
Título: Group-specific amplification of cDNA from DRB1 genes. Complete coding sequences of partially defined alleles and identification of t he new alleles DRB1*040602, DRB1*111102, DRB1*080103 and DRB1*0113.Human Immunol 67, 1008-1016, 2006.
14. Gil J, Busto EM, Garcillán B, Chean C, Gar´cia-Rodríguez MC, Díaz-Adelante A, Navarro J, Reiné J, Mencía A, Gurbindo D, Beléndez C, Gordillo I, Duchniewicz M, Höne K,García-Sánchez F, Fernández-Cruz E, López-Granados E, Schamel WW, Moreno-Pelayo MA, Recio MJ, Reguerio JR..A Leary mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ-Tγδ+B+NK+ human SCID. J Clin Invest. 121, 3872-3876, 2011.
15. Jurado M, Algrora M, García-Sánchez F, Vico S, Rodríguez E, Pérez S, Barbolla L.Automated processing ofwhole blood units: operational value and in vitro quality of final blood components. Blood Transfusion 10, 63-71, 2012.